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Cell biology, microbiology, ecology, biodiversity, species data, evolutionary biology
23,009 datasets
A dataset likely contains results from medicinal chemistry experiments on novel antibacterial compounds. The data describes the synthesis and testing of metronidazolyl vinylthiazolidionyl tetrahydroberberines (MVTs), including minimum inhibitory concentrations (MICs), hemolysis, cytotoxicity, and biofilm eradication assays. The dataset was authored by Yu Zhou and last updated on 2026-05-26.
Three Senna seedling populations were measured north of a reserve fence in 1997 to study grazing effects, with two populations enclosed by protective fences and one left unprotected. The dataset has been updated through versions, with the latest version 2.1 released in 2026. Data was digitized and organized by the Terrestrial Ecosystem Research Network to comply with FAIR and TERN standards.
TGB Osborn (Koonamore) Vegetation Reserve data comprises a multi-decade collection of flora and fauna observations from a 390-hectare grazing exclusion site in arid South Australia. The dataset is organized into sub-collections including vegetation quadrats, photopoints, species-specific assessments, and fauna surveys. This long-term study was initiated in 1925 to research the ecology of arid zone vegetation and the effects of grazing.
Four paired transects in the TGB Osborn (Koonamore) Vegetation Reserve provide a rare long-term record of saltbush (Atriplex spp.) encroachment from the eastern and southern boundaries. Data from 1989, 2003, 2008, and 2014 track the spread of Atriplex vesicaria and A. stipitata, following a standardized plant census. This dataset represents a reactivated monitoring program, with early historical data from the reserve's founding not available digitally.
26 survey instances from 1940 to 2014 track the abundance of Cassia (Senna artemesioides) in a 7150 m2 area of the TGB Osborn Vegetation Reserve. The dataset includes counts of individuals and their life stage (adult or juvenile). This version 2.1 release is managed by the Terrestrial Ecosystem Research Network, with data originally digitized from field sheets.
Francois D. Rouleau published a dataset on figshare in 2026 detailing PCR cycles used in a study of Pneumocystis jirovecii, an opportunistic fungal pathogen. The research involved deep mutational scanning of the dihydrofolate reductase (DHFR) protein expressed in yeast to measure the effects of amino-acid substitutions on function and resistance to antifolate drugs. The dataset, 16.7 KB in size, supports a machine-learning framework for predicting resistance mutations.
Francois D. Rouleau published a dataset on figshare in May 2026 detailing strains used in a study of Pneumocystis jirovecii. The dataset likely contains information on fungal strains engineered for deep mutational scanning of the DHFR protein to model resistance to antifolate drugs like methotrexate and trimethoprim. The dataset is 9.5 KB in size and is available in XLSX format.
Francois D. Rouleau published details on plasmids used in a study of Pneumocystis jirovecii dihydrofolate reductase (PjDHFR) on 2026-05-27. The dataset, shared under a CC-BY-4.0 license, is a 10.7 KB XLSX file. It supports research on antifungal drug resistance by detailing genetic constructs for deep mutational scanning experiments in yeast.
Francois D. Rouleau published details on oligonucleotides used in a 2026 study of Pneumocystis jirovecii dihydrofolate reductase (PjDHFR). The dataset supports a deep mutational scanning experiment to measure the effects of all single amino-acid substitutions on enzyme function and resistance to antifolate drugs. Experimental results were integrated with biophysical modeling and a random forest model to predict resistance mutations.
Experimental data from a deep mutational scanning study of the dihydrofolate reductase (DHFR) enzyme from the fungal pathogen Pneumocystis jirovecii. The dataset, created by Francois D. Rouleau and last updated in May 2026, measures the effects of single amino-acid substitutions on enzyme function and resistance to the antifolate methotrexate, used to train a random forest model for predicting resistance to related drugs like trimethoprim.
A large set of human bone samples from medieval cemeteries in south-western Norway links microscopic preservation analysis with metagenomic results. Detailed microscopic analyses show diverse levels of preservation, and the extent of bioerosion is correlated with microbiome composition and environmental factors. The dataset was authored by Damla Kaptan and is available under a CC-BY-4.0 license.
MALT Sequence statistics from a study correlating microscopic bone preservation with metagenomic analyses. The dataset likely contains results from human bone samples collected from medieval cemeteries in south-western Norway. It was authored by Damla Kaptan and last updated on 2026-05-27.
A KrakenUniq abundance matrix from a study of human bone samples from medieval cemeteries in south-western Norway. The dataset correlates microscopic bone preservation levels with metagenomic analyses and environmental factors. It was authored by Damla Kaptan and last updated on 2026-05-27.
Marine imagery and oceanographic data collected during a 31-day voyage in May 2024 from Hobart to Sydney. The Australian Ocean Data Network provides video and stereo stills of benthic habitats captured by the MNF Deep Towed camera. This data supports a long-term study of ecosystem change in the southeast marine region over 25 years.
Imagery and data collected during the Marine National Facility RV Investigator voyage IN2023_V01 from January 25 to March 2, 2023. The dataset includes video, stereo stills, and navigational data from the Cape Darnley region of East Antarctica. It was collected using the MNF Deep Towed camera (DTC) system.
Tabular data from a study investigating the role of the functional amyloid Cystatin-related epididymal spermatogenic (CRES) protein in brain extracellular matrix (ECM) structure and behavior. The dataset, authored by Alejandra Gomez and shared on figshare, compares CRES knockout (KO) and wild-type (WT) mice, analyzing sex-specific changes in hippocampal and cortical ECM and behavioral deficits. It was last updated on 2026-05-27.
Net Primary Production (NPP) surfaces were generated for nine Earth Observing System Land Validation Sites across the Americas from 2000 to 2004. The dataset, produced by NASA's BigFoot project, models NPP at a 25-meter resolution for 7x7 km areas using the Biome-BGC process model calibrated with field and tower data. It specifically archives data for Northern Old Black Spruce and Harvard Forest sites from 2001.
A 2024 spatial dataset from the NSW Department of Climate Change, Energy, Environment and Water assessing the ecological value of river reaches. It combines scores for naturalness, diversity, distinctiveness, and vital habitat into a standardized index from 0 to 1 for each River Style reach. The distinctiveness criterion was updated in 2018 using predicted threatened fish species distribution data.
28 semi-structured interviews and 11 Q-methodology surveys trace motivational pathways for rock climbers reporting bat evidence. The dataset, authored by Emily Gross and last updated in May 2026, likely contains qualitative and quantitative data from a mixed-methods study. It identifies five motivational pathways, including ecological, science, community, access, and incentive-based drivers.
HDM1005 (poterepatide), a novel GLP-1/GIP dual agonist, was engineered via computational alanine scanning and rational acylation design. The dataset, authored by Nan Zhang and last updated in May 2026, likely contains results from molecular dynamics simulations and MMGBSA calculations comparing HDM1005 to Tirzepatide.