Murine Gut Microbiome 16S Sequencing in DSS-Induced Colitis

16S rDNA Amplicon Sequencing of the Intestinal Contents in a Murine Model of Ulcerative colitis contains sequencing data from the small intestinal contents of mice. The data compares a non-modeled control group to groups with DSS-induced colitis, including groups treated with the drugs FTY720 and AMD3100. This dataset is intended to evaluate changes in the gut microbiota following different drug treatments.

Use Cases

• Comparing gut microbiota composition between healthy and DSS-induced colitis mice.
• Evaluating the effect of FTY720 treatment on microbial communities in a colitis model.
• Assessing the effect of AMD3100 treatment on microbial communities in a colitis model.
• Investigating drug-induced shifts in specific bacterial taxa within the small intestine.

Strengths

• Dataset is openly licensed under CC-BY-4.0, facilitating reuse.
• Data size is explicitly stated as 192,969,560 bytes, indicating a substantial sequencing output.
• Experimental design includes multiple treatment groups (control, DSS model, FTY720, AMD3100) for comparative analysis.

Limitations

• Column names and exact row counts are not provided, limiting understanding of data structure.
• The dataset's primary file format is RAR, which may require additional software to access.
• Metadata is incomplete, lacking information on the author's organization and specific sequencing details.

Provenance

Source

Hengjun Huang

Collection Method

16S rDNA amplicon sequencing performed on murine small intestinal contents.

Freshness

Last updated on 2026-03-20.