Utrogestan vs Duphaston: Patient-Level IVF Outcomes and Sleep Quality
by Phi Thi, Tu Anh / Harvard Dataverse·Updated 2d ago
Available on 1 platform
Sign in to view source links and access this dataset
Description
De-identified patient records from a single-center retrospective cohort study comparing two oral progestins for pituitary suppression in progestin-primed ovarian stimulation. The dataset includes women under 40 undergoing IVF/ICSI with a freeze-all strategy, covering demographic, hormonal, embryological outcomes, and Pittsburgh Sleep Quality Index scores. Author Phi Thi, Tu Anh published the data on Harvard Dataverse in July 2026 to accompany a manuscript and support full reproduction of reported statistical analyses.
Use Cases
Modeling luteinizing hormone trajectories across stimulation days using linear mixed-effects models.
Comparing embryological outcomes like oocyte retrieval and blastocyst development between two progestin regimens.
Assessing the impact of treatment on patient-reported sleep quality using the Pittsburgh Sleep Quality Index.
Investigating factors associated with protocol conversion to a GnRH antagonist regimen via logistic regression.
Strengths
Includes patient-level data for a specific clinical comparison of oral micronized progesterone (200 mg) and dydrogesterone (30 mg).
Covers multiple data domains: baseline demographics, serial hormone measurements (LH, estradiol, progesterone), stimulation parameters, and embryological outcomes.
Supports reproduction of advanced statistical analyses mentioned, including inverse probability of treatment weighting and negative binomial regression.
Limitations
Column-level documentation is absent; field semantics must be inferred after download.
Row count is unknown, which may limit suitability assessment.
Data is from a single tertiary care center, which may limit generalizability.
Provenance
Source
Harvard Dataverse, author Phi Thi, Tu Anh.
Collection Method
Retrospective cohort study using de-identified patient records from a tertiary care assisted reproductive technology center.
Freshness
Last updated 2026-07-22 19:38:26; freshness should be verified.
Geography
Single-center study; specific location not stated.
License is unknown; terms of use should be verified before download.