Tingjun Liu published research findings on figshare in April 2026. The 5.6 MB dataset includes PDF and DOCX files detailing a study on Coxsackievirus B3 (CVB3) infection in viral myocarditis. The work uses single-cell RNA sequencing to investigate the suppression of PINK1-mediated mitophagy and its role in viral replication.
Use Cases
- Study the correlation between impaired mitophagy and cardiomyocyte pathology based on single-cell RNA sequencing results
- Analyze the role of the viral non-structural protein 3C in degrading MAVS based on the described mechanistic pathway
- Investigate the transcription factor FOSL1 as a negative regulator of PINK1 transcription based on promoter binding evidence
- Model the 3C/FOSL1/PINK1/MAVS signaling axis in CVB3 pathogenesis based on the proposed regulatory loop
Strengths
- Dataset is 5.6 MB, facilitating quick download and review
- Files are available in PDF and DOCX formats, which are widely accessible
- License is CC-BY-4.0, allowing for open sharing and reuse
Limitations
- Row count is unknown, which may limit suitability assessment
- Column-level documentation is absent; field semantics must be inferred after download
- The dataset consists of research documents; raw sequencing or tabular data is not explicitly mentioned
Provenance
- Source
- figshare
- Collection Method
- Research likely involved single-cell RNA sequencing and molecular biology techniques.
- Freshness
- Last updated 2026-04-26 18:20:03; freshness should be verified