A Boundary Element Framework for Microneedle-Assisted Nanoparticle Photothermal Hypertherm

A computational dataset from figshare authored by Mohamed Abdelsabour Fahmy, last updated in May 2026. It contains results from a boundary element method simulation for photothermal hyperthermia therapy in multilayer skin tissue with a superficial tumor. The model extends the Pennes bioheat equation to include nanoparticle heating, laser absorption, and temperature-dependent thermal damage.

Use Cases

• Optimizing laser exposure parameters for tumor treatment based on simulated thermal-dose accumulation.
• Estimating required nanoparticle concentration for effective therapy based on simulated heating profiles.
• Evaluating healthy-tissue safety margins in photothermal therapy based on simulated spatial temperature distributions.
• Studying the influence of tumor geometry and skin layer interfaces on treatment efficacy based on the boundary element framework.

Strengths

• Model considers multiple physical factors including non-uniform skin structure, perfusion, metabolism, laser heating, and nanoparticle heat generation.
• The boundary element formulation reduces the need for full-domain meshing, which the description suggests improves computational efficiency.
• The dataset is licensed under CC-BY-4.0, allowing for open sharing and modification.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The data is a 3.2 MB ZIP file, suggesting a relatively small-scale simulation output.

Provenance

Source

figshare

Collection Method

Computational simulation using a boundary element method (BEM) approach.

Freshness

Last updated 2026-05-29 22:12:55; freshness should be verified.