Mouse Brain Active Neuron Coordinates and Connectivity Matrices

1.3 GB of spatial coordinates and connectivity matrices for neurons across multiple mouse brains, published by Guanhua Sun in 2026. The data includes neuron counts per anatomical region and matching with spatial transcriptomic data for neurotransmitter information. Raw microscopy images used for segmentation are also provided in a downsampled format.

Use Cases

• Mapping neuron locations to anatomical regions based on the Allen Brain Atlas coordinates.
• Analyzing inter-region connectivity patterns using the provided active connectivity matrices.
• Correlating neuronal activity with neurotransmitter expression using matched spatial transcriptomic data.
• Developing or validating neuron segmentation algorithms using the accompanying raw image files.

Strengths

• Data is anchored to a standard anatomical reference, the Allen Brain Atlas.
• Includes multiple data modalities: spatial coordinates, region counts, connectivity matrices, and source images.
• Accompanying Python code (active_neuron_connectivity.py) is provided for analysis reproducibility.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The original high-resolution image files (>2 TB each) are not included, only downsampled versions.

Provenance

Source

figshare

Collection Method

Likely derived from microscopy imaging and computational segmentation, with region matching to the Allen Brain Atlas.

Freshness

Last updated 2026-06-02 18:48:10; freshness should be verified.