Meta-Analysis of Red Blood Cell Distribution Width in COPD Clinical Outcomes

A systematic review and meta-analysis of 41 articles with 19,518 participants, published by Yi Zeng on figshare. The work integrates data from PubMed, Embase, Cochrane Library, and Web of Science up to October 2024. It quantifies the association between red blood cell distribution width and outcomes in chronic obstructive pulmonary disease.

Use Cases

• Validate the prognostic value of RDW for COPD mortality based on reported AUC and odds ratios.
• Compare RDW levels between stable and acute exacerbation COPD patients using the standardized mean differences provided.
• Assess the relationship between RDW and COPD complications using the reported effect sizes.
• Inform clinical trial design by leveraging the synthesized evidence on RDW as a risk predictor.

Strengths

• Analysis is based on 41 articles and 19,518 participants, providing a substantial evidence base.
• Reports specific statistical measures including standardized mean differences, odds ratios, and AUC values with confidence intervals.
• Systematic search protocol covering multiple major databases up to a specific date (October 2024).

Limitations

• The primary data file is a 12.1 MB DOCX document; the underlying raw or tabular data for the meta-analysis is not directly provided.
• Row count and column-level documentation for any underlying datasets are unknown.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Systematic literature search and meta-analysis of published studies.

Time Range

Studies included up to 11 October 2024.

Freshness

Last updated 2026-04-17 10:40:03