68Ga-PDT02: PET/CT Radiotracer Data for uPAR Imaging

Gallium-68-labeled PDT02 peptide demonstrates specific tumor accumulation with a mean uptake of 2.88%ID/mL at 30 minutes post-injection. The dataset likely contains results from in vitro assays and in vivo PET imaging in mice, supporting the tracer's potential for visualizing urokinase-type plasminogen activator receptor expression. Author Gangzhong Zhou published this data on figshare in May 2026.

Use Cases

• Evaluate radiotracer binding affinity based on the reported KD value of 531.3 nM
• Analyze tumor-to-background contrast based on biodistribution data showing rapid clearance from non-target tissues
• Compare in vitro uptake between cell lines based on the described higher uptake in uPAR-positive MKN45-huPAR cells versus A549 cells
• Assess pharmacokinetic profiles based on the described rapid renal excretion and low blood retention

Strengths

• Includes specific quantitative metrics such as KD = 531.3 nM and mean tumor uptake of 2.88%ID/mL
• Describes both in vitro (cell assays) and in vivo (mouse xenograft) experimental validation
• Data is associated with a specific, novel tracer (68Ga-PDT02) for a defined target (uPAR)

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data scale is limited (338.3 KB), suggesting a focused experimental dataset rather than a large-scale collection

Provenance

Source

figshare

Collection Method

Data likely originates from laboratory experiments involving peptide synthesis, radiolabeling, and imaging studies.

Freshness

Last updated 2026-05-07 00:44:52; freshness should be verified