A Pd-Catalyzed Route to Neutral and Anionic Aminated Carboranes

A dataset describing chemical synthesis protocols for functionalizing boron-rich carborane clusters with nitrogen-containing groups. The data was authored by Ya-Nan Wang and published on figshare in May 2026. It details methods for mono- and diamination, oxidative cyclization, and controlled deboronation reactions.

Use Cases

• Optimizing Pd-catalyzed cross-coupling conditions for carborane amination based on described ligand and condition parameters.
• Designing new carborane-fused heterocycles based on the described oxidative cyclization protocol.
• Synthesizing anionic nido-carborane derivatives for medicinal chemistry applications based on the described controlled deboronation methods.

Strengths

• Describes a general protocol for mono- and vicinal diamination of ortho-carborane.
• Includes methods for generating previously inaccessible trisubstituted nido-carboranes via anodic oxidation.

Limitations

• Dataset size is only 14.9 KB, indicating a very limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Likely contains experimental data from chemical synthesis research.

Freshness

Last updated 2026-05-16 14:15:09; freshness should be verified.