A review paper authored by S P H Alexander from the University of Nottingham, identifying opportunities for drug discovery in the treatment of COVID-19. The paper provides a rational roadmap for pharmacology, assessing the scope for targeting key host and viral targets for drug repurposing and novel discovery. It outlines strategies for rapid clinical translation and future-proofing against drug resistance and emerging viral threats.
Use Cases
- Identifying drug repurposing candidates based on the analysis of host and viral targets described in the review.
- Informing long-term drug discovery strategies based on the proposed multi-pronged approach targeting a short-list of entities.
- Structuring therapeutic research agendas for future viral threats based on the coherent strategy outlined in the paper.
Strengths
- Authored by a researcher from a recognized institution (University of Nottingham).
- Provides a structured, dual-strategy roadmap covering both immediate repurposing and long-term novel discovery.
Limitations
- Row count is unknown, which may limit suitability assessment.
- Column-level documentation is absent; field semantics must be inferred after download.
- Last update date is unknown; freshness unverified.
Provenance
- Source
- University of Nottingham
- Collection Method
- Academic review paper.