Systematic Review of Probiotic Effects on Depression and Anxiety

A systematic review by Miryam de Souza Minayo analyzing nine randomized double/triple blind placebo-controlled clinical trials. The review aims to understand the effects of probiotics on depression, anxiety, and psychological stress, sourced from PubMed, Scopus, and Lilacs. Seven of the nine analyzed studies found positive results in at least one of the measured items.

Use Cases

• Meta-analysis of probiotic efficacy based on results from nine clinical trials.
• Studying the relationship between the gut microbiome and psychiatric disorders based on the described gut-brain axis concept.
• Identifying research gaps for future clinical trials based on the review's conclusion that more rigorous studies are needed.

Strengths

• Analysis is based on nine randomized double/triple blind placebo-controlled clinical trials, a rigorous study design.
• The review followed PRISMA recommendations for systematic reviews and meta-analyses.
• Seven out of nine analyzed studies reported positive results, providing a basis for further investigation.

Limitations

• Row count and specific data columns are unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Last update date is unknown; freshness unverified.

Provenance

Source

paperswithcode

Collection Method

Systematic search in PubMed, Scopus, and Lilacs databases following PRISMA guidelines.