Systematic Review of Pharmacotherapy for Post-Traumatic Attention Deficits

Sonya Kim's systematic review synthesizes evidence on pharmacological treatments for adults with attention deficits following traumatic brain injury. The review includes 29 studies across five drug classes and 14 medications, sourced from Ovid MEDLINE and Cochrane Library up to December 2024. It assesses evidence levels using the Sackett framework and study quality with the Cochrane Risk of Bias tool and PEDro scale.

Use Cases

• Compare the efficacy of different drug classes like methylphenidate and donepezil based on the synthesized evidence.
• Assess the quality and risk of bias in clinical trials for post-traumatic attention treatments based on the described methodology.
• Identify research gaps for future clinical trials based on the review's recommendations for standardized outcome measures.
• Evaluate the level of evidence for specific medications like MLC901 or anticonvulsants based on the reported findings.

Strengths

• Includes 29 studies, providing a structured synthesis of existing evidence.
• Covers a wide range of 14 medications across five different drug classes.
• Uses established quality assessment tools (Cochrane Risk of Bias, PEDro scale) and evidence framework (Sackett).

Limitations

• The dataset is a 108.2 KB DOCX file, indicating a limited scope focused on review text rather than raw clinical data.
• Row count and column-level documentation are absent; field semantics must be inferred after download.
• Data may reflect publication or selection bias inherent to the systematic review methodology.

Provenance

Source

figshare, author Sonya Kim

Collection Method

Systematic review of Ovid MEDLINE and Cochrane Library (1946–December 2024).

Time Range

Literature covered from 1946 to December 2024.

Freshness

Last updated 2026-05-21 11:02:16; freshness should be verified.