AcrIIA7: Protein Structure Data for CRISPR-Cas Inhibition

2.3 MB of structural data for the AcrIIA7 protein, which hijacks tracrRNA to block CRISPR-Cas systems. The dataset, authored by Hyun Ho Park, includes atomic coordinates in PDB format and structural factors in MTZ format. It was last updated on May 1, 2026.

Use Cases

• Analyzing protein-RNA interaction interfaces based on the 3D structural data.
• Conducting molecular dynamics simulations using the atomic coordinates.
• Performing structural comparisons with other anti-CRISPR (Acr) proteins.
• Validating or refining the AcrIIA7 structural model with the provided structural factors.

Strengths

• Includes both atomic coordinates (PDB) and experimental structural factors (MTZ), providing a complete structural dataset.
• Released under the permissive CC-BY-4.0 license, allowing for broad reuse and modification.
• File size of 2.3 MB indicates a focused, manageable dataset for structural analysis.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for certain computational tasks.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Likely derived from experimental structural determination methods such as X-ray crystallography.

Time Range

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Freshness

Last updated 2026-05-01 07:01:16; freshness should be verified.

Geography

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