ACTG ART Interruption Studies: Viral Rebound Data from 235 Participants

ACTG Statistical and Data Analysis Center provides data from 235 participants across 6 Analytic Treatment Interruption (ATI) studies. The dataset includes HIV-1 RNA level data for all participants and HIV-persistence measures for a subset of 124 individuals. These data were examined in multiple statistical and modeling papers from 2016 to 2025.

Use Cases

• Modeling time to viral rebound after treatment interruption based on participant data.
• Conducting causal mediation analysis on the effects of pre-ATI HIV-persistence measures on ATI outcomes.
• Using the data as historical controls for contemporary ATI studies, excluding participants on NNRTIs as recommended.

Strengths

• Data from 235 participants across 6 distinct clinical studies.
• Includes a subset of 124 participants with measured HIV-persistence data.
• Referenced in multiple peer-reviewed statistical methods papers from 2016 to 2025.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The 486.6 KB size suggests a limited scope of variables.

Provenance

Source

ACTG Statistical and Data Analysis Center

Collection Method

Collected from 6 ACTG (AIDS Clinical Trials Group) studies with Analytic Treatment Interruption (ATI).

Freshness

Last updated 2026-03-18 16:40:32; freshness should be verified.