Cu2 Complex Cytotoxicity Data for Synergistic Ferroptosis and Apoptosis

A 1.6 KB CSV file containing data related to the cytotoxicity of a pyridine-hydrazone-derived Cu(II) complex (Cu2). The dataset, authored by Hai-Qun Zhang and last updated on 2026-04-21, likely contains measurements from experiments investigating the compound's mechanism of action in disrupting endoplasmic reticulum and mitochondrial networks to induce cell death in cancer models.

Use Cases

• Analyzing the relationship between glutathione depletion and hydroxyl radical generation based on the described redox cycle.
• Modeling the self-amplifying ROS–Ca2+ feedback loop based on described mitochondrial dysfunction and ER stress.
• Evaluating the antitumor and antimetastatic efficacy of copper complexes based on the described cervical cancer model results.
• Comparing the selective cytotoxicity of different pyridine-hydrazone Cu(II) complexes (Cu1–Cu7) based on the described screening.

Strengths

• Dataset is small (1.6 KB), facilitating quick download and initial inspection.
• License is clearly specified as CC-BY-NC-4.0, defining reuse terms.
• Last update timestamp is precise (2026-04-21 05:29:53), indicating recent activity.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Freshness

Last updated 2026-04-21 05:29:53; freshness should be verified.