Supplementary Data for STAT3/HDAC Inhibitor Effects in Solid Tumor Models

Supplementary Material 1 contains densitometric quantification data from Western blot analyses and cell viability assays for a study on the radiosensitizing effects of a dual-target inhibitor. The data includes measurements of protein levels like p-STAT3 and Ac-H3/H4, and cell viability results from CCK8 assays across A549, MDA-MB-231, and B16 cell lines. Qi Wang published this dataset on figshare in April 2026 under a CC-BY-4.0 license.

Use Cases

• Analyze dose-response relationships for cell viability based on CCK8 assay results.
• Compare protein expression levels, such as p-STAT3 and Ac-H3/H4, across different cell lines.
• Evaluate the impact of a compound on colony formation and cell migration rates.
• Associate changes in DNA repair protein levels (e.g., DNA-PKcs, γ-H2AX) with treatment effects.

Strengths

• Data is derived from three independent experiments, as stated in the description.
• Includes statistical significance annotations (P-values) for comparisons.
• The dataset is 1010.7 KB in size, indicating a focused scope.

Limitations

• Row count and column-level documentation are unknown.
• The data is supplementary to a specific study, limiting its standalone scope.
• Freshness should be verified as the last update is projected for 2026.

Provenance

Source

figshare

Collection Method

Likely generated as supplementary experimental data for a research publication.

Freshness

Last updated 2026-04-18 03:40:10