Holstein Cattle Milk Transcriptome Variants for Subclinical Mastitis Response

Additional file 1 contains 13 Excel tables detailing milk traits and transcriptome-derived variants linked to subclinical intramammary infection in Holstein cattle. The 9.1 MB dataset, authored by Alice Vanzin and last updated in May 2026, includes statistics on milk yield, composition, and udder health, alongside unique genetic variants and annotated quantitative trait loci (QTLs) for different infection status groups. It is shared under a CC-BY-4.0 license on figshare.

Use Cases

• Identify candidate genetic markers for mastitis resistance based on variants uniquely identified in infection-negative groups.
• Predict functional consequences of genetic variants based on the described high-impact annotations.
• Map genomic regions associated with udder health traits using the annotated and enriched QTLs within 2 Kb intervals.
• Compare host immune response signatures between different pathogen groups (e.g., Prototheca spp. vs. Streptococcus agalactiae) based on the group-specific variant tables.

Strengths

• Dataset is structured across 13 distinct tables, providing organized data on multiple aspects of the study.
• Includes predicted high-impact consequences for identified genetic variants, adding a functional annotation layer.
• File size of 9.1 MB suggests a detailed, multi-sheet Excel workbook.
• Clear temporal metadata with a specific last update timestamp of 2026-05-17 03:50:08.

Limitations

• Row count is unknown, which may limit suitability assessment for large-scale analyses.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data scope is limited to Holstein cattle, which may not generalize to other breeds.

Provenance

Source

figshare, authored by Alice Vanzin.

Collection Method

Likely derived from transcriptome sequencing and phenotypic analysis of dairy cattle.

Freshness

Last updated 2026-05-17 03:50:08; freshness should be verified.