Table S11: Significantly Altered Metabolites in COVID-19 Patients by Disease Severity

Additional file 12 from a multi-omics study reveals interferon response heterogeneity and links lipid metabolism to immune alterations in severe COVID-19. The 304.5 KB XLSX file, authored by Ronaldo Lira-Junior and last updated in May 2026, contains a list of metabolites that differ significantly between mild and severe cases. It is shared under a CC-BY-4.0 license on figshare.

Use Cases

• Identify metabolic biomarkers for severe COVID-19 based on the list of significantly altered metabolites.
• Investigate links between lipid metabolism and immune dysregulation in severe disease as suggested by the study title.
• Validate or compare findings on interferon response heterogeneity in COVID-19 patient cohorts.
• Integrate metabolite data with other omics layers for systems biology analysis of COVID-19.

Strengths

• The data is directly linked to a peer-reviewed multi-omics study, providing research context.
• The file is shared under a permissive CC-BY-4.0 license for reuse.
• The dataset is focused on a specific, clinically relevant comparison: mild vs. severe COVID-19.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale analyses.
• The 304.5 KB size indicates a limited scope, likely containing summary results rather than raw patient-level data.

Provenance

Source

figshare

Collection Method

Likely generated as supplementary material for a published multi-omics research study.

Freshness

Last updated 2026-05-30 03:35:30