GLYATL1: Epigenetic and Metabolic Markers in Luminal Breast Cancer Cell Lines

Supplementary Table 10 provides median values from EpiTOF experiments on MCF7 parental, long-term estrogen deprived (LTED), and LTED GLYATL1 knockout cell lines. The dataset, authored by Janina Müller and last updated on 2026-04-30, contains median values for indicated epigenetic marks from two replicate experiments. Raw z-score data for individual cells is available separately at Zenodo.

Use Cases

• Compare epigenetic profiles between parental and drug-resistant cell lines based on median EpiTOF values.
• Investigate the role of GLYATL1 in metabolic and epigenetic regulation based on knockout cell line data.
• Validate findings from raw single-cell z-score data using the provided summary statistics.

Strengths

• Data is derived from two replicate EpiTOF experiments, suggesting internal validation.
• Dataset is small (13.8 KB) and in XLSX format, facilitating quick inspection and analysis.
• Raw single-cell data is available via a provided Zenodo DOI for deeper investigation.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is a supplementary table; its scope is limited to the specific cell lines and marks studied.

Provenance

Source

figshare, supplementary material from a research publication.

Collection Method

EpiTOF (Epigenetic Time-of-Flight) mass cytometry experiments on cultured cell lines.

Freshness

Last updated 2026-04-30 04:13:34; freshness should be verified.