Illumina Sequencing Artifact Mismatch Counts and Proportions

Supplementary Information 1 from a 2026 study on a recurrent Illumina sequencing artifact. The dataset, authored by Beverly J. Fu, contains counts and proportions of single-base mismatches at different pileup coverages for each sample, stored in a 357.1 KB XLSX file.

Use Cases

• Quantifying sequencing artifact rates based on mismatch counts and proportions.
• Assessing the impact of pileup coverage on artifact detection based on the described data structure.
• Benchmarking somatic variant callers against known artifact profiles derived from the mismatch data.
• Calibrating error models for two-color fluorescent dye chemistry sequencing platforms.

Strengths

• Data is directly linked to a peer-reviewed study on a specific sequencing artifact.
• File size is 357.1 KB, making it quick to download and inspect.
• Published under a permissive CC-BY-4.0 license for reuse.

Limitations

• Row count and specific column definitions are unknown, requiring manual inspection after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, associated with a research publication.

Collection Method

Likely derived from analysis of Illumina sequencing runs to characterize artifacts.

Freshness

Last updated 2026-05-28 04:34:21; freshness should be verified.