Leptospira Small RNA Differential Expression Across Conditions and Strains

Ellie J Putz provides normalized read counts and differential expression analysis for small RNAs in Leptospira borgpetersenii serovar Hardjo. The data includes four biological replicates across two strains and two temperature conditions, with contrasts for specific comparisons. It was last updated on June 1, 2026.

Use Cases

• Identify significantly differentially expressed small RNAs based on adjusted p-value and fold-change thresholds.
• Compare small RNA expression profiles between the JB197 and HB203 strains at the same temperature.
• Analyze temperature-dependent small RNA expression changes within the same bacterial strain.
• Validate small RNA conservation across different Leptospira genomes using mapping results.

Strengths

• Includes four biological replicates per condition, which can improve statistical confidence.
• Differential expression analysis uses a defined significance threshold (adjusted p-value < 0.05 and Log2FC > 1.585).
• Provides contrasts mapped to two different reference genomes for comparative analysis.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for specific analytical needs.

Provenance

Source

Ellie J Putz via figshare.

Collection Method

Likely derived from RNA sequencing experiments on Leptospira strains under controlled conditions.

Freshness

Last updated 2026-06-01 03:19:23; freshness should be verified.