TUSC7: 17 Candidate lncRNA Mutations for NSCLC Biomarker Research

Figshare hosts a shortlist of 17 long non-coding RNA (lncRNA) mutations meeting specific CADD PHRED>20 and FATHMM-MKL>0.98 filters. The data was contributed by author Pablo Martin-Lopez and last updated on April 11, 2026. It is supplementary material for a study on TUSC7 as a diagnostic and therapeutic biomarker in non-small cell lung cancer.

Use Cases

• Prioritizing high-impact lncRNA mutations for experimental validation based on CADD PHRED and FATHMM-MKL scores.
• Analyzing mutation overlap across different lncRNA transcripts for functional studies.
• Training or benchmarking variant prioritization models for cancer genomics.

Strengths

• Contains 17 pre-filtered candidate mutations meeting stringent bioinformatic thresholds.
• Data is openly licensed under CC-BY-4.0 for reuse and redistribution.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 1.0 KB, indicating limited scope.

Provenance

Source

Pablo Martin-Lopez via figshare.

Collection Method

Likely derived from genomic sequencing and computational filtering as supplementary material for a research publication.

Freshness

Last updated 2026-04-11 03:36:55; freshness should be verified.