Proteomic Profiles from At-Home Dried Blood Samples for 16 Donors

Proteomic assay results from dried blood samples collected from 16 individuals using Tasso M20 devices, compared against plasma and serum from the same donors. The dataset includes SomaScan Assay measurements for over 800 proteins and models predicting complete blood counts. Weston J. Smith authored the dataset, which was last updated on 2026-05 04.

Use Cases

• Comparing protein measurement consistency between dried blood spots and traditional plasma/serum matrices based on the cross-sectional analysis described.
• Developing models to predict clinical hematology parameters like complete blood counts from proteomic data based on the generated models mentioned.
• Identifying cell-secreted or surface proteins measurable in dried blood samples based on the over 800 proteins characterized.
• Evaluating the feasibility of patient-centric, at-home sample collection for affinity proteomics studies based on the described methodology.

Strengths

• Includes matched-sample data from 16 donors across three sample types: dried blood spots, plasma, and serum.
• Identifies over 800 proteins that can be measured in both plasma and dried blood spots.
• Contains generated predictive models for complete blood counts, with results indicating DBS data may provide more accurate predictions than plasma.

Limitations

• Row count is unknown, which may limit suitability assessment for statistical modeling.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small at 812.7 KB, indicating a limited scope of 16 donors.

Provenance

Source

figshare

Collection Method

Dried blood samples were collected by Tasso M20 devices and analyzed by the SomaScan Assay; results were compared to plasma and serum from the same donors.

Time Range

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Freshness

Last updated 2026-05-04 14:55:14; freshness should be verified.

Geography

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