Proteomic Profiles from At-Home Dried Blood Samples for 16 Donors

A 2026 study by Weston J. Smith compares proteomic measurements from at-home dried blood samples, plasma, and serum. The dataset contains SomaScan Assay results for over 800 proteins and complete blood count (CBC) data from 16 individuals. Models predicting CBCs from the assay data are also included.

Use Cases

• Comparing protein measurement consistency between dried blood, plasma, and serum matrices as described.
• Developing predictive models for complete blood counts (CBCs) based on proteomic assay data.
• Analyzing the subset of over 800 proteins actively secreted or found on cellular surfaces that are measurable in both plasma and dried blood.
• Investigating the clinical utility of patient-centric, at-home sample collection methods for affinity proteomics.

Strengths

• Includes matched data from three sample types (dried blood, plasma, serum) for 16 donors, enabling direct comparison.
• Contains measurements for over 800 proteins identified as measurable in both plasma and dried blood.
• Models generated from the data demonstrate that dried blood sample (DBS) data can more accurately predict complete blood counts than plasma data.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small in scale at 342.3 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Dried blood samples were collected from 16 individuals using Tasso M20 devices and analyzed via the SomaScan Assay.

Time Range

2026

Freshness

Last updated 2026-05 14:55:13; freshness should be verified.

Geography

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