AFADESI-MSI Spatial Metabolomics Data of the Aging Mouse Brain
by Waleed Alam·Updated 22d ago
71.1 MB2files
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Description
71.1 MB of processed spatial metabolomics data from mouse brain sections across three aging stages (6, 15, and 21 months). The dataset, authored by Waleed Alam and supporting a 2026 manuscript, includes region-specific metabolite abundance matrices provided separately for positive and negative ion acquisition modes.
Use Cases
Analyze region-specific metabolite abundance changes across aging stages based on the provided intensity matrices.
Compare metabolic profiles acquired in positive versus negative ion modes as described.
Integrate spatial metabolomics data with other omics datasets for multi-omics studies of brain aging.
Train models to predict metabolite distribution patterns in different brain regions.
Validate findings from the associated manuscript on nucleotide metabolic reprogramming in aging.
Strengths
Data covers three distinct aging stages (6, 15, and 21 months), providing a temporal progression.
Includes processed metabolite intensity information for individual brain regions, suggesting structured spatial analysis.
Data are provided independently for both positive and negative ion acquisition modes, enabling comparative analysis.
Supports a specific 2026 manuscript, indicating a research-driven context.
Limitations
Column-level documentation is absent; field semantics must be inferred after download.
Row count is unknown, which may limit suitability assessment.
Data may reflect methodological bias inherent to the AFADESI-MSI technique used.