Air Pollution Exposure Induces Vascular Endothelial Cell Dysfunction via Elevated Circulat

A panel study of eight college students traveling from Qingdao to Shijiazhuang, China, where pollutant levels were higher, collected serum samples at multiple time points. The dataset contains integrated proteomic, metabolomic, and transcriptomic analyses from 2026, authored by Jianzhong Zhang. It is a 4.6 MB XLSX file shared under a CC-BY-NC-4.0 license.

Use Cases

• Identify molecular mediators like F2 (prothrombin) based on proteomic profiling and network analysis described in the study
• Analyze perturbations in bile acid biosynthesis and arginine-proline metabolism based on the metabolomic results
• Investigate endothelial cell activation pathways based on the transcriptomic profiling of endothelial cells
• Correlate molecular responses with specific pollutant exposures (PM2.5, PM10, SO2, NO2, CO) based on the panel study design

Strengths

• Integrates three omics layers (proteomic, metabolomic, transcriptomic) for a multi-faceted analysis
• Data is based on a controlled panel study with serum samples collected at multiple time points
• File is 4.6 MB and in the accessible XLSX format

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• The sample size is limited to eight participants

Provenance

Source

figshare, authored by Jianzhong Zhang

Collection Method

Serum samples collected from a panel study of eight college students, analyzed via ex vivo biosensor assays and multiomics profiling

Time Range

The study appears to be recent, but specific collection dates are not provided in the input.

Freshness

Last updated 2026-04-27 14:08:59; freshness should be verified

Geography

China (travel route from Qingdao to Shijiazhuang)