All data from <i>Limosilactobacillus reuteri</i><i> </i>promotes melatonin release from hu

Erika Nachman's research data, published on figshare in May 2026, investigates the impact of carbon sources and metal cofactors on the 5'ectonucleotidase (5'NT) activity of Limosilactobacillus reuteri strains. The data shows zinc is an essential cofactor and demonstrates how the bacterium stimulates melatonin release from pediatric human intestinal organoids in a 5'NT-dependent manner. It includes comparisons of melatonin secretion levels induced by different L. reuteri strains.

Use Cases

• Modeling the relationship between bacterial nutrient utilization and enzymatic activity based on carbon source data.
• Investigating the role of zinc as a cofactor for bacterial 5'NT activity.
• Analyzing strain-specific differences in probiotic-induced melatonin secretion.
• Studying 5'NT-dependent signaling pathways in human intestinal organoid models.

Strengths

• Data is associated with a specific, peer-reviewed research hypothesis on probiotic mechanisms.
• Includes comparative analysis between two L. reuteri strains (DSM 17938 and DSM 32846).
• Released under the permissive CC-BY-4.0 license for reuse.

Limitations

• Row count and file format are unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect experimental bias inherent to the specific organoid model and conditions used.

Provenance

Source

figshare, author Erika Nachman.

Collection Method

Likely contains experimental measurements from laboratory research on bacterial cultures and organoids.

Time Range

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Freshness

Last updated 2026-05-04 22:33:43; freshness should be verified.

Geography

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