AlphaFold 3 Models for Break-Induced Replication Proteins

AlphaFold 3-generated protein structure models in PDB format for a study on break-induced replication (BIR). The data includes models of the Pol32 subunit of DNA polymerase delta and its interaction with the RPA protein complex. The dataset was authored by Antony Oliver and deposited on figshare in 2026.

Use Cases

• Visualize predicted protein structures based on the provided PDB files.
• Analyze protein-protein interaction interfaces described for Pol32 and RPA.
• Compare structural models of RPA-binding modules across different proteins like Pif1 and Mph1.
• Investigate the structural impact of phosphorylation at Thr256 and Thr257 on Pol32's affinity for RPA.

Strengths

• Models are generated by AlphaFold 3, a state-of-the-art protein structure prediction tool.
• Data is provided in the standard Protein Data Bank (PDB) format, compatible with many visualization and analysis tools.
• Released under the permissive CC-BY-4.0 license for open reuse.

Limitations

• Description metadata is limited; actual data quality requires manual inspection after download.
• Row count is unknown, which may limit suitability assessment.
• The author notes that amino-acid numbering in the model files may not correspond to the full-length parent protein.

Provenance

Source

Antony Oliver via figshare.

Collection Method

Computational models generated by AlphaFold 3.

Freshness

Last updated 2026-05-07 10:51:53; freshness should be verified.