AlphaFold3 Predicted Structures for NBS1-Artemis Protein Fragment

AlphaFold3 models predict the 3D structure of the NBS1-Artemis protein fragment spanning residues 529-559. The models were generated by Chi-Lin Tsai using the AlphaFold3 web server in November 2023 and published in April 2026. The dataset contains structural data in JSON and CIF formats.

Use Cases

• Analyze predicted 3D coordinates and atomic positions for the NBS1-Artemis fragment to study protein-protein interactions.
• Validate AlphaFold3's performance on specific protein domains by comparing predicted residue distances and angles.
• Use the predicted per-residue confidence scores (pLDDT) to assess model reliability for different regions of the fragment.
• Extract structural features like secondary structure elements from the model for input into machine learning pipelines.

Strengths

• Models generated by the state-of-the-art AlphaFold3 software version from November 2023.
• Data is openly shared under a permissive CC-BY-4.0 license.
• Provides structural data in both JSON and CIF formats, offering flexibility for different analysis tools.

Limitations

• Dataset is small at 5.9 MB, containing predictions for a single, specific 31-residue protein fragment.
• No experimental validation data (e.g., from X-ray crystallography) is provided to benchmark the model accuracy.
• The temporal coverage is a single prediction snapshot from late 2023, not a time series.

Provenance

Source

Chi-Lin Tsai, via the figshare repository.

Collection Method

Generated computationally using the AlphaFold3 web server (version AlphaFold-beta-20231127).

Time Range

Prediction generated November 2023.

Freshness

Last updated on the platform in April 2026, though the underlying prediction was made in November 2023.