ALS GWAS: Summary-Level Association Data for 740,868 Participants

740,868 participants (31,254 cases; 709,614 controls) contributed to this summary-level genome-wide association study for Amyotrophic Lateral Sclerosis (ALS). The dataset includes chromosomal location, alleles, association metrics, and statistical significance. Fengzhen Liu published the data under a CC-BY-4.0 license on figshare, last updated on 2026-05-20.

Use Cases

• Identify genetic variants associated with ALS risk based on association metrics and P-values.
• Calculate polygenic risk scores based on effect allele and effect size.
• Perform meta-analysis or replication studies using summary-level statistics.
• Validate candidate loci in ALS based on chromosomal location and allele information.

Strengths

• Large sample size of 740,868 participants, including 31,254 cases.
• Includes key GWAS variables: chromosomal location, alleles, effect size, standard error, and P-value.
• Published under a permissive CC-BY-4.0 license.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Freshness should be verified as the last update date is in the future (2026-05-20).

Provenance

Source

figshare

Freshness

Last updated 2026-05-20 07:06:39.