Amyloid-β and δ-COP Co-assembly Molecular Interaction Data

5.2 MB of molecular simulation data explores the direct interaction between amyloid-β (Aβ) and coatomer subunit delta (δ-COP). The dataset likely contains structural coordinates from experiments and simulations, including a high-affinity binding site involving specific peptide sequences. It was authored by Anastasia Vlachou and uploaded to figshare in March 2026.

Use Cases

• Validate protein-protein interaction models based on the described high-affinity binding site.
• Analyze molecular docking simulations based on the δ-COP and Aβ peptide sequences mentioned.
• Investigate the role of the I422 residue in δ-COP based on the comparison with T422 highlighted in the description.

Strengths

• Data size is 5.2 MB, indicating a focused and manageable dataset.
• Includes results from both experiments and simulations, providing complementary insights.
• The description details specific peptide sequences (e.g., DGEYRHDS, DAEFRHDS) involved in the interaction.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (5.2 MB), which may limit the scope of analysis.

Provenance

Source

figshare

Collection Method

Likely contains data from molecular experiments and computational simulations.

Freshness

Last updated 2026-03-19 14:36:24; freshness should be verified.