Aggregated Influenza A Virus Morbidity and Titer Measurements from 728 Infected Ferrets

A dataset from the U.S. Department of Health & Human Services aggregates raw data from 728 ferrets inoculated with 126 unique influenza A viruses under a uniform protocol. This collection represents the largest publicly available dataset of in vivo-generated IAV infection outcomes on a per-individual ferret level. The data was published in a 2024 Scientific Data descriptor and is associated with multiple research publications.

Use Cases

• Modeling associations between viral titer measurements and disease outcomes based on serial morbidity data.
• Training machine learning models for influenza A virus risk assessment using in vivo ferret data.
• Improving the normalization and interpretation of morbidity data in mammalian models of viral disease.
• Studying virus replication and transmissibility of human and zoonotic influenza strains.

Strengths

• Contains data from 728 individual ferrets, a scale described as the largest publicly available dataset of its kind.
• Aggregates results from 126 unique influenza A viruses under a uniform experimental protocol, reducing methodological variability.
• Data is supported by multiple peer-reviewed publications, including a dedicated data descriptor.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for specific modeling tasks.

Provenance

Source

NCIRD/ID/IPB/Pathogenesis Laboratory Team, U.S. Department of Health & Human Services

Collection Method

Serially collected measurements from ferrets inoculated with influenza A viruses under a uniform protocol.

Time Range

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Freshness

Last updated 2026-03-10 15:36:22.826158; freshness should be verified.

Geography

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