Transepithelial Crosslinking Efficacy in Keratoconus Patients, 49 Eyes from Brazil

49 eyes from 37 patients aged 10 to 50 years were analyzed in a 2017 retrospective study at the Instituto Panamericano da Visão in Goiânia, Brazil. The research evaluated the safety and efficacy of Transepithelial Crosslinking (CXL) for progressive keratoconus, measuring visual acuity, astigmatism, and pachymetry over 12 months. The dataset was authored by Roseane Lucena Marquez and is available via paperswithcode.

Use Cases

• Modeling visual acuity improvement over time based on pre- and post-operative measurements mentioned in the description
• Analyzing the correlation between patient age and treatment efficacy for keratoconus
• Evaluating the statistical significance of changes in astigmatism and pachymetry following CXL treatment
• Comparing treatment outcomes between different demographic groups (e.g., sex) within the study cohort

Strengths

• Includes longitudinal data with measurements at preoperative, 1-month, 6-month, and 12-month intervals
• Study reports specific, statistically significant results (p-values) for key clinical outcomes like UDVA and CDVA
• Describes a standardized treatment protocol using the Avedro KXL system with specific energy and riboflavin parameters

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Data may reflect geographic bias inherent to a single-center study in Brazil

Provenance

Source

Roseane Lucena Marquez, via paperswithcode

Collection Method

Retrospective cross-sectional study

Time Range

2017

Geography

Goiânia, Goiás, Brazil