Prunus Amygdalus Extract Antihyperglycemic Activity via DPP-IV Inhibition

A pharmacological study from Sungkyunkwan University investigates the antihyperglycemic effect of Prunus amygdalus extract on Streptozotocin-induced diabetic rats. The dataset likely contains experimental results including blood glucose levels, biochemical parameters, and antioxidant activity percentages. It was authored by Richa Sachan and is available via paperswithcode.

Use Cases

• Validate natural product efficacy for diabetes based on reported blood glucose level reductions.
• Train predictive models for DPP-IV inhibition based on antioxidant activity data.
• Correlate biochemical parameter alterations with histopathological observations of pancreatic β-cells.

Strengths

• Reports specific quantitative results, such as DPPH scavenging activity ranging from 40.0% to 90.0%.
• Includes results from multiple experimental approaches: oral glucose tolerance tests, biochemical assays, and histopathology.
• Study design involves dose-dependent analysis at 50, 100, and 200 mg/kg.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect the specific experimental bias inherent to a single pharmacological study.

Provenance

Source

Sungkyunkwan University

Collection Method

Experimental validation via animal models and in-silico molecular docking.

Geography

Jammu and Kashmir, India (study context)