Genetic Polymorphism Data for Hepatocellular Carcinoma from Arunachal Pradesh and Sikkim

222 blood samples from patients and healthy controls were analyzed for polymorphisms in IDH2, KRAS1, TP53, and BRAF2 genes using PCR-RFLP and Sanger sequencing. The data was collected via a structured questionnaire for demographic and clinical information from individuals in Arunachal Pradesh and Sikkim, India. The dataset was authored by Chetan Chauhan and last updated on figshare in April 2026.

Use Cases

• Identifying genetic risk factors for hepatocellular carcinoma based on demographic and clinical variables mentioned in the description
• Validating PCR-RFLP mutation detection methods through Sanger sequencing results for KRAS1 and IDH2
• Analyzing associations between lifestyle factors like tobacco exposure and genetic polymorphisms in HCC patients
• Studying regional and ethnic variation in mutation patterns for key oncogenes and tumor suppressors

Strengths

• Includes data from 222 individual patient and control blood samples
• Genetic analysis verified by two methods: PCR-RFLP and Sanger sequencing
• Demographic and clinical information collected via a structured questionnaire

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect geographic bias inherent to the specific regions of Arunachal Pradesh and Sikkim

Provenance

Source

figshare

Collection Method

Blood samples collected, genomic DNA extracted, gene regions amplified, and analyzed via PCR-RFLP and Sanger sequencing.

Time Range

null

Freshness

Last updated 2026-04-14 06:34:09; freshness should be verified

Geography

Arunachal Pradesh and Sikkim, India