COVID-19 Outcomes for Patients with Overweight/Obesity-related Hypertension, 439 Records

439 adult patients with overweight/obesity and hypertension were admitted to the University of Iowa Hospitals and Clinic between March 1 and December 7, 2020. The retrospective cohort study by Elham Shams assesses the association between pre-hospitalization ARB/ACEI use and COVID-19 mortality and severity. Results suggest patients prescribed these medications exhibited lower mortality and a shorter hospital length of stay.

Use Cases

• Train models to predict COVID-19 mortality risk based on patient medication history and clinical markers mentioned in the description
• Analyze associations between RAAS antagonist use and hospital length of stay for patients with obesity-related hypertension
• Study the relationship between pre-existing conditions and ICU admission or mechanical ventilation requirements during COVID-19 hospitalization

Strengths

• Study includes 439 patient records with specific inclusion criteria (BMI ≥ 25 kg/m2, hypertension, COVID-19 diagnosis).
• Analysis uses multivariable logistic regression with defined statistical thresholds (two-sided alpha = 0.05).
• Outcomes are evaluated across multiple severity markers: mortality, length of stay, ICU admission, and use of supplemental oxygen, mechanical ventilation, and vasopressors.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown for the underlying dataset, which may limit suitability assessment.
• Data may reflect temporal and geographic bias inherent to a single hospital study from March to December 2020.

Provenance

Source

Elham Shams, via paperswithcode.

Collection Method

Retrospective cohort study of patients admitted to University of Iowa Hospitals and Clinic.

Time Range

March 1 to December 7, 2020

Geography

University of Iowa Hospitals and Clinic, United States