ABO and Rh Blood Groups Association with Hepatitis C Virus Infection: A Meta-Analysis

A systematic review and meta-analysis investigating associations between ABO/Rh blood groups and Hepatitis C virus infection. The analysis includes 38 studies with 3,404,016 participants, sourced from databases like PubMed and Scopus up to January 2025. It was authored by Wanatsanan Chulrik and published under a CC-BY-4.0 license.

Use Cases

• Assessing the association of blood group B with HCV infection risk based on the reported odds ratio of 1.11.
• Evaluating the lack of significant association for blood groups A, AB, O, and Rh factor with HCV infection based on pooled odds ratios.
• Examining methodological consistency in epidemiological studies based on the described risk of bias assessment and heterogeneity analysis.
• Planning future multi-regional studies based on the identified limitations regarding study design variability.

Strengths

• Includes a large participant pool of 3,404,016 individuals from 38 studies.
• Reports specific statistical measures, including odds ratios with 95% confidence intervals for each blood group.
• Follows a registered protocol (PROSPERO CRD420250635714) and includes subgroup, sensitivity, and publication bias analyses.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is a 54.0 MB DOCX file, which is a small document format not directly machine-readable as structured data.
• Row count is unknown, which may limit suitability assessment for quantitative analysis.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of studies from PubMed, Scopus, Embase, and MEDLINE.

Time Range

Studies from database inception to 23 January 2025.

Freshness

Last updated 2026-04-27 05:39:49; freshness should be verified.