Association of BMP15 and GDF9 with Litter Size in Livestock: A Review

A literature review by Majeed Ajafar investigates the association of bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) with litter size in livestock. The review compiles information on how these growth factors, part of the TGF-β superfamily, regulate ovulation and fertility. It provides information on their role as potential biological markers for improving livestock fertility.

Use Cases

• Identifying genetic markers for fertility based on the review of BMP15 and GDF9 roles
• Informing selective breeding programs for litter size based on the described biological mechanisms
• Supporting meta-analysis on the TGF-β superfamily's role in livestock reproduction

Strengths

• Focuses on two specific, significant growth factors (BMP15 and GDF9) for fertility regulation
• Describes a clear biological mechanism linking gene function to a key economic trait (litter size)
• Source is an Open Access (green) publication, suggesting availability

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Last update date is unknown; freshness unverified

Provenance

Source

Majeed Ajafar via paperswithcode

Collection Method

Literature review