Asymmetric Aminocatalysis and Iodine Catalysis Reaction Data

A sequential catalytic system combining asymmetric aminocatalysis with iodine catalysis is described. The dataset, 27.9 MB in size, was authored by Pooja Goyal and last updated in June 2026. It likely contains experimental results for the synthesis of chiral spirodihydrobenzofuran-pyrazolones.

Use Cases

• Modeling reaction yields based on described Michael/iodization/nucleophilic substitution sequences.
• Predicting enantioselectivity for spiro-quaternary stereocenter formation mentioned in the description.
• Analyzing the scalability of one-pot catalytic methods under mild reaction conditions.
• Studying the reactivity of less reactive electrophiles as described in the protocol.

Strengths

• Dataset is 27.9 MB in size, indicating a specific scope.
• The description details a mechanistically distinct synthetic pathway.
• Reaction conditions are described as mild and scalable.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Likely contains experimental data from the described catalytic synthesis.

Freshness

Last updated 2026-06-02 16:08:42; freshness should be verified