Ralstonia Solanacearum Quorum Sensing Inhibition by 4-Aminobenzoic Acid

Experimental data from figshare, published by chuanwang Yao on 2026-04-27, investigates the inhibition of bacterial virulence. The dataset includes TIF and XLSX files totaling 3.0 MB, documenting the effects of 4-aminobenzoic acid (PABA) on Ralstonia solanacearum's quorum sensing system.

Use Cases

• Analyzing the binding interaction between PABA and the transcription regulator RaaR based on experimental results
• Modeling the inhibition of extracellular polysaccharide production and biofilm formation in R. solanacearum
• Studying point mutations in RaaR residues F137 and I270 to understand ligand binding
• Evaluating the reduction of quorum sensing signaling molecule expression levels
• Developing novel antibacterial treatment strategies based on anthranilic acid signaling interference

Strengths

• Includes experimental data on specific molecular interactions, such as PABA binding to RaaR
• Provides results on measurable biological functions like EPS production, biofilm formation, and motility
• Dataset is licensed CC-BY-4.0, allowing for open reuse

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Data may reflect experimental bias inherent to the specific laboratory study

Provenance

Source

figshare

Collection Method

Laboratory experimental research

Freshness

Last updated 2026-04-27 09:04:51; freshness should be verified