Healthy Equine Skin Single-Cell RNA-Seq Data from Two Horses

A high-quality single-cell RNA sequencing dataset characterizing cellular diversity in healthy equine skin. Amanda Raine generated this foundational resource from skin biopsies of two clinically healthy horses, processed using the Singleron GEXSCOPE platform and aligned to the EquCab3.0 genome. The dataset, updated in April 2026, supports studies of equine skin biology, disease comparisons, and investigations of immune responses and tissue homeostasis.

Use Cases

• Establish a transcriptional reference landscape for healthy equine skin based on single-cell RNA-seq data
• Compare cellular profiles with disease states mentioned in the description
• Investigate immune responses and tissue homeostasis in equine skin
• Support dermatological condition research using the provided integrated RDS data

Strengths

• Data generated from two clinically healthy horses in biological duplicate
• Sequenced on an Illumina NovaSeq X with paired-end 150 bp reads
• Aligned to the EquCab3.0 reference genome using the CeleScope pipeline

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect bias inherent to figshare

Provenance

Source

figshare

Collection Method

Skin biopsies collected from the mane region, dissociated into single-cell suspensions, and sequenced on the Singleron GEXSCOPE platform.

Freshness

Last updated 2026-04-10 11:17:49