Acetyl Tributyl Citrate Toxicity Data for Pulmonary Fibrosis Research

56.5 MB of research data from a study investigating the role of Acetyl Tributyl Citrate in idiopathic pulmonary fibrosis. The dataset includes results from computational toxicology, machine learning on transcriptome data, molecular docking simulations, and a pilot experiment in bleomycin-induced fibrotic mice. It was authored by Dajia Fu and last updated on 2026-05-15.

Use Cases

• Validate predicted compound-target interactions based on molecular docking simulations.
• Analyze transcriptome data for core target identification in idiopathic pulmonary fibrosis.
• Correlate intratracheal ATBC dose with lung pathology and MMP1 expression trends from mouse model experiments.

Strengths

• 56.5 MB of multi-format data including PDF, XLSX, and CSV files.
• Data integrates computational predictions with experimental results from a mouse model.

Limitations

• Row count and column-level documentation are unknown, requiring manual inspection after download.
• The exploratory pilot experiment suggests a limited sample size for the in vivo component.

Provenance

Source

Dajia Fu via figshare

Collection Method

Generated through computational toxicology, machine learning analysis of transcriptome data, molecular docking, and a mouse model experiment.

Freshness

Last updated 2026-05-15 05:30:55; freshness should be verified.