ATBC Inhalation Exposure Data for Pulmonary Fibrosis Research via MMP1/CTSB

A 76.2 MB research dataset from figshare, last updated April 4, 2026. It contains computational toxicology predictions, transcriptome analysis, molecular docking simulations, and experimental results from a pilot study on bleomycin-induced fibrotic mice. The dataset was authored by dajia Fu and is licensed under CC-BY-4.0.

Use Cases

• Validate computational toxicology predictions for chemical targets based on the described methodology.
• Analyze core targets from idiopathic pulmonary fibrosis (IPF) clinical transcriptome data using machine learning.
• Simulate compound-target interactions for acetyl tributyl citrate (ATBC) via molecular docking data.
• Correlate intratracheal ATBC dose effects with lung pathology and MMP1 expression trends from the pilot experiment.

Strengths

• Includes multiple data modalities (PDB, PNG, TXT, R) supporting a multi-method research approach.
• Dataset size is 76.2 MB, indicating a substantive collection of research files.
• License is CC-BY-4.0, permitting open sharing and adaptation with attribution.

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality and completeness require manual inspection.
• The dataset appears to be a single research output; its generalizability may be limited.

Provenance

Source

figshare

Collection Method

Generated via computational toxicology predictions, transcriptome screening, molecular docking, and a pilot animal experiment.

Time Range

The dataset itself has no stated temporal coverage for the underlying phenomena.

Freshness

Last updated 2026-04-04 07:14:45; freshness should be verified.

Geography

Geographic coverage of the data is not specified.