Ancient P. falciparum mtDNA Sequences from the Medici Family and Other Studies

Multiple sequence alignment files contain Plasmodium falciparum mitochondrial DNA sites recovered from Cardinal Giovanni de' Medici (1543–1562) and other Plasmodium sequences from different studies. The ancient P. falciparum sequences were obtained through a non-competitive mapping procedure against a reference genome. The dataset was authored by Alexander Ochoa and last updated on April 17, 2026.

Use Cases

• Phylogenetic analysis based on ancient and modern Plasmodium falciparum mtDNA sequences.
• Demographic analysis of P. falciparum based on genetic variation data.
• Comparative genomics of Plasmodium species based on multiple sequence alignments.
• Historical pathogen reconstruction based on ancient DNA from 16th-century remains.

Strengths

• Includes ancient P. falciparum sequences from a historically significant individual, Cardinal Giovanni de' Medici.
• Provides multiple sequence alignment files for comparative phylogenetic analysis.
• Uses a specific P. falciparum mtDNA reference genome (GenBank: LR605957.1, 3D7 isolate).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Ancient sequences obtained through non-competitive mapping against a reference genome; other sequences retrieved from different studies.

Time Range

Includes data from the 16th century (1543–1562) and other unspecified studies.

Freshness

Last updated 2026-04-17 23:01:04; freshness should be verified.

Geography

Italy (based on the origin of the Medici remains).