Experimental data from an integrative study investigating the multi-target protective mechanisms of Xiao-Yao-San against drug-induced liver injury. The dataset includes results for preliminary concentration screening (IC50 and Csafe), APAP-induced HepG2 injury model establishment, cytoprotective effects, and comprehensive hepatoprotective efficacy evaluation. It was authored by Zi-Yi Zheng and last updated on 2026-04-11.
Use Cases
- Modeling dose-response relationships based on IC50 and Csafe concentration screening data
- Evaluating cytoprotective efficacy of compounds like beta-sitosterol and luteolin against APAP-induced injury
- Comparing hepatoprotective effects across multiple treatment groups described in the experimental design
Strengths
- Experimental design includes six distinct treatment groups for comparative analysis
- Data covers multiple validation stages: concentration screening, model establishment, and efficacy evaluation
- Published under a CC-BY-4.0 license, permitting reuse with attribution
Limitations
- Column-level documentation is absent; field semantics must be inferred after download
- Row count is unknown, which may limit suitability assessment
- Description metadata is limited; actual data quality requires manual inspection after download
Provenance
- Source
- figshare
- Collection Method
- Cell experimental validation data from a computational-experimental study.
- Time Range
- null
- Freshness
- Last updated 2026-04-11 08:47:12; freshness should be verified
- Geography
- null