DBV Activates Macrophage HIF-1α/MMP9 Axis in Severe SFTS: Multi-Omics and Clinical Data

2.7 MB of research data supporting a study on Severe Fever with Thrombocytopenia Syndrome (SFTS). The dataset combines clinical data with multi-omics analyses and in vitro/in vivo experiments to investigate endothelial barrier disruption. It was authored by Jianmei Zhou and last updated on 2026-05-28.

Use Cases

• Validate key mediators of endothelial barrier disruption based on multi-omics analyses mentioned in the description
• Correlate clinical outcomes with molecular pathways based on combined clinical and experimental data
• Train models to predict disease severity based on identified key mediators and mechanisms
• Reproduce in vitro and in vivo experimental findings using the provided raw data

Strengths

• Data supports a systematic evaluation of endothelial barrier function in patients, as stated in the description
• Combines multiple data types: clinical data, multi-omics analyses, and experimental results
• Published under a permissive CC-BY-4.0 license for reuse

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The 2.7 MB size suggests a relatively small dataset, potentially limiting statistical power

Provenance

Source

figshare

Collection Method

Systematic evaluation using clinical data, multi-omics analyses, and in vitro/in vivo experiments.

Freshness

Last updated 2026-05-28 15:21:15; freshness should be verified