Molecular Mechanisms of Polypills in Cardiovascular Disease Treatment, 5.0 MB

A 5.0 MB dataset from figshare, last updated in May 2026, contains raw data from a study on polypills for hypertension and heart failure. The research, authored by jia hu, employed bibliometric and network pharmacology analyses to identify key biological targets and pathways. Findings suggest polypills exert effects through coordinated action of multiple signaling pathways like MAPK and PI3K/Akt.

Use Cases

• Validate molecular docking results for the identified key target AKT1 based on the study's network pharmacology.
• Conduct pathway enrichment analysis based on the mentioned MAPK, PI3K/Akt, and Ras signaling pathways.
• Perform bibliometric trend analysis on polypill research for cardiovascular disease prevention and treatment.
• Train predictive models for drug-target interactions using the identified network pharmacology data.

Strengths

• Data is openly licensed under CC-BY-4.0, facilitating reuse and sharing.
• The 5.0 MB file size indicates a manageable dataset for local analysis.
• The description provides a clear research context involving bibliometric and network pharmacology methods.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Likely contains raw data from bibliometric analysis and network pharmacology studies.

Freshness

Last updated 2026-05-09 04:51:37; freshness should be verified.