Meta-Analysis of Sodium Fluorescein Efficacy in Glioma Surgery

A meta-analysis by 海健 曾 synthesizes evidence from seven cohort studies involving 488 patients to evaluate sodium fluorescein-guided resection for glioma. The dataset likely contains statistical results, including odds ratios and confidence intervals, comparing fluorescein-guided surgery to white-light surgery on outcomes like gross total resection and recurrence. It supports the conclusion that fluorescein guidance improves resection rates and reduces recurrence without increasing mortality or complications.

Use Cases

• Evaluating the efficacy of sodium fluorescein for improving gross total resection rates in glioma surgery.
• Assessing the safety profile of fluorescein-guided surgery by analyzing mortality and complication data.
• Comparing recurrence odds between fluorescein-guided and white-light surgical techniques.
• Conducting secondary statistical analysis on pooled results from the included cohort studies.

Strengths

• Includes data from 7 cohort studies with a pooled patient count of 488.
• Provides specific statistical measures (e.g., OR=3.50 for gross total resection).
• Released under a permissive CC-BY-4.0 license, facilitating reuse.

Limitations

• Column names and row counts are not provided, limiting understanding of the data structure.
• The description references a search date of 'Nov 31, 2025', which is an invalid date, casting doubt on temporal precision.
• The dataset appears to be a single analysis file; underlying patient-level data from the original studies is not included.

Provenance

Source

海健 曾

Collection Method

Meta-analysis of studies from PubMed, Embase, Web of Science, and Cochrane Library.

Time Range

Studies searched up to November 2025.

Freshness

Last updated on 2026-03-21.

Geography

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