Gut Microbiota and Metabolite Data from a Mouse Colitis Study

A 93.0 KB Excel dataset from figshare contains integrated transcriptomics, 16S rRNA sequencing, and untargeted metabolomics data from a mouse model of DSS-induced colitis. The data was generated by author 东京 刘 to investigate the therapeutic effects of aucubin and the role of the gut microbiota-derived metabolite equol. The dataset was last updated on 2026-05-14.

Use Cases

• Analyze associations between microbial taxa and host gene expression based on integrated 16S rRNA and transcriptomic data
• Identify microbial metabolites correlated with colitis severity based on untargeted metabolomics data
• Validate computational predictions of drug-microbe interactions using fecal microbiota transplantation results
• Model arginine metabolism pathways based on the described ASS1/iNOS axis

Strengths

• Data integrates three omics layers: transcriptomics, 16S rRNA sequencing, and untargeted metabolomics
• The study design includes fecal microbiota transplantation and direct metabolite administration for causal validation
• Dataset is openly licensed under CC-BY-4.0 for reuse

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The 93.0 KB file size suggests a limited scope, likely containing summary or processed results rather than raw sequencing reads

Provenance

Source

figshare

Collection Method

Data generated from a mouse model of DSS-induced colitis treated with aucubin, analyzed via integrated omics.

Freshness

Last updated 2026-05-14 13:51:15; freshness should be verified