Genome-Wide Association Statistics for Basal Cell Carcinoma Susceptibility

Genome-wide association studies were performed on 17,416 basal cell carcinoma cases and 375,455 controls. The dataset contains summary statistics from these GWAS, integrated with multi-omics data including expression and methylation quantitative trait loci. It was authored by C. Adolphe and published on figshare in April 2026.

Use Cases

• Identify single nucleotide polymorphisms associated with basal cell carcinoma risk using GWAS summary statistics.
• Integrate blood- and skin-specific expression quantitative trait loci data to prioritize candidate susceptibility genes.
• Correlate GWAS loci with methylation quantitative trait loci data to explore epigenetic regulatory mechanisms.
• Perform meta-analysis by combining these summary statistics with other skin cancer GWAS datasets.

Strengths

• Large control cohort of 375,455 individuals.
• Analysis integrates multi-omics data (eQTLs and mQTLs) for functional interpretation.

Limitations

• Specific sample size for cases (17,416) is moderate for a complex trait GWAS.
• Unknown row count and specific column structure for the summary statistics file.

Provenance

Source

C. Adolphe via figshare.

Collection Method

Genome-wide association study analysis followed by statistical integration of population-based multi-omics data.

Freshness

Last updated in April 2026.